CyFlow Kappa-LC FITC (RUO)
| 品番 | AD141331 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu KAPPA-LC FITC,A8B5 | ||
| 包装単位 | 100 tests | ||
| 濃度 | - | ||
| 推奨使用量 | - | ||
| 容量 | 2 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Human | レーザー | Blue |
| 抗原 | κ light chains | 最大蛍光波長 | 518 nm |
| クローン | A8B5 | 最大励起波長 | 490 to 495 nm |
| ホスト | Mouse | 標識/Format | FITC |
| アイソタイプ | IgG1 | 研究分野 | Immunoglobulins |
| クローナリティ | monoclonal | アプリケーション | - |
Anti-Hu KAPPA-LC FITC,A8B5
特異性
The mouse monoclonal antibody A8B5 recognizes κ light chains (22.5 kDa) of immunoglobulins.
抗原情報
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (κ and λ; both having a molecular weight of 22.5kDa). κ and λ consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of κ to λ is 70:30.
利用方法
The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20 µl reagent / 100 µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Avilés-Salas A, Chanona-Vilchis JG, Candelaria-Hernández MG, Peña-Torres Mde L, Cuéllar-Mendoza ME: Presentación inicial de un linfoma plasmablástico como tumor ovárico. Ginecol·Obstet·Mex. 2012·Jun; 80(6):430‑4. <·PMID:·22826973·>
• Di Bartolo DL, Hyjek E, Keller S, Guasparri I, Deng H, Sun R, Chadburn A, Knowles DM, Cesarman E: Role of defective Oct‑2 and OCA‑B expression in immunoglobulin production and Kaposi's sarcoma‑associated herpesvirus lytic reactivation in primary effusion lymphoma. J·Virol. 2009·May; 83(9):4308‑15. <·PMID:·19224997·>
• Diaz de Domingo NB, Lardo MM, Romero Artaza J, Merelli A, Carbia CD, Sánchez Avalos JC: Aplicacion de tecnicas inmunocitoquimicas para el diagnostico de neoplasias hematologicas. Medicina·(B·Aires). 1999; 59(1):11‑6. <·PMID:·10349112·>
• Franklin EC: Structure and function of immunoglobulins. Acta·Endocrinol·Suppl·(Copenh). 1975; 194:77‑95. <·PMID:·47690·>
• Konig A, Wennemuth G, Soyer HP, Hoffmann R, Happle R, Krause W: Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma. Eur·J·Dermatol. 1999·Jan-Feb; 9(1):29‑31. <·PMID:·9920983·>
• Scheeren FA, Diehl SA, Smit LA, Beaumont T, Naspetti M, Bende RJ, Blom B, Karube K, Ohshima K, van Noesel CJ, Spits H: IL‑21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis. Blood. 2008·May·1; 111(9):4706‑15. <·PMID:·18296629·>