特異性

The mouse monoclonal antibody 01G recognizes membrane-bound form of HLA-G (full-length HLA-G1) antigen, but not soluble forms. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

抗原情報

利用方法

保存方法

Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.

安定性情報

Do not use after expiration date stamped on vial label.

レファレンス

• Ishitani A, Sageshima N, Lee N, Dorofeeva N, Hatake K, Marquardt H, Geraghty DE: Protein Expression and Peptide Binding Suggest Unique and Interacting Functional Roles for HLA‑E, F and G in Maternal‑Placental Immune Recognitions. J·Immunol. 2003; 171:1376. <·PMID:·12874228·>
• Polakova K, Bandzuchova E, Hofmeister V, Weiss EH, Hutter H, Russ G: Binding analysis of HLA‑G specific antibodies to hematopoietic cells isolated from leukemia patients. Neoplasma. 2003; 50(5):331‑8. <·PMID:·14628085·>
• Polakova K, Krcova M, Kuba D, Russ G: Analysis of HLA‑G expression in malignant hematopoetic cells from leukemia patients. Leuk·Res. 2003·Jul; 27(7):643‑8. <·PMID:·12681364·>
• Polakova K, Russ G: Expression of the non‑classical HLA‑G antigen in tumor cell lines is extremely restricted. Neoplasma. 2000; 47(6):342‑8. <·PMID:·11263857·>
• Real LM, Cabrera T, Canton J, Oliva R, Ruiz-Cabello F, Garrido F: Looking for HLA‑G expression in human tumours. J·Reprod·Immunol. 1999·Jul; 43(2):263‑73. <·PMID:·10479062·>
• Real LM, Cabrera T, Collado A, Jimenez P, Garcia A, Ruiz-Cabello F, Garrido F: Expression of HLA G in human tumors is not a frequent event. Int·J·Cancer. 1999·May·17; 81(4):512‑8. <·PMID:·10225437·>
• Wiendl H, Feger U, Mittelbronn M, Jack C, Schreiner B, Stadelmann C, Antel J, Brueck W, Meyermann R, Bar-Or A, Kieseier BC, Weller M: Expression of the immune‑tolerogenic major histocompatibility molecule HLA‑G in multiple sclerosis: implications for CNS immunity. Brain. 2005·Nov; 128(11):2689‑2704. <·PMID:·16123145·>