CyFlow HLA-Class I Purified (RUO)
| 品番 | BY003346 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu HLA-ClAss I PURI,MEM-81 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 1 mg/ml | ||
| 推奨使用量 | - | ||
| 容量 | 0.1 ml | ||
| 関連製品 (アイソタイプコントロール) |
Mouse IgG1 Purified (BJ561896) Mouse IgG1 Purified (AS224818) |
||
| 反応性|交差吸着 | Human | レーザー | - |
| 抗原 | HLA-Class I | 最大蛍光波長 | - |
| クローン | MEM-81 | 最大励起波長 | - |
| ホスト | Mouse | 標識/Format | Purified |
| アイソタイプ | IgG1 | 研究分野 | MHC |
| クローナリティ | monoclonal | アプリケーション | - |
Anti-Hu HLA-ClAss I PURI,MEM-81
特異性
The mouse monoclonal antibody MEM-81 recognizes classical MHC Class I molecules in native cell-surface forms. MHC Class I molecules (MHC Class Ia) are expressed on the surface of human nucleated cell types.
抗原情報
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant β2-microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
利用方法
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Frank I, Stoiber H, Godar S, Stockinger H, Steindl F, Katinger HW, Dierich MP: Acquisition of host cell-surface-derived molecules by HIV-1. AIDS. 1996·Dec; 10(14):1611-20. <·PMID:·8970680·>
• Valenzuela NM, Mulder A, Reed EF: HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcγRs.. J·Immunol. 2013·Jun·15; 190(12):6635-50. <·PMID:·23690477·>