CyFlow IgM PE-Cy5 (RUO)
| 品番 | CD447273 | ||
|---|---|---|---|
| 抗体名 | Anti-Hu IGM PE-CY5,CH2 | ||
| 包装単位 | 0.1 mg | ||
| 濃度 | 0.1 mg/ml | ||
| 推奨使用量 | - | ||
| 容量 | 1 ml | ||
| 関連製品 (アイソタイプコントロール) |
- | ||
| 反応性|交差吸着 | Human | レーザー | Blue, Green, Yellow |
| 抗原 | IgM | 最大蛍光波長 | 670 nm |
| クローン | CH2 | 最大励起波長 | 496 nm, 565 nm |
| ホスト | Mouse | 標識/Format | PE-Cy5 |
| アイソタイプ | IgG1 | 研究分野 | Immunoglobulins |
| クローナリティ | monoclonal | アプリケーション | - |
Anti-Hu IGM PE-CY5,CH2
特異性
The mouse monoclonal antibody CH2 recognizes Fc fragment of human immunoglobulin M (IgM).
抗原情報
Immunoglobulin M (IgM) is produced as a 900 kDa pentamer, which is an efficient complement binder. This antibody type is produced initially in the immune response and it is the first immunoglobulin class to be synthesized by a fetus or newborn. IgM antibodies do not cross the placenta. IgM concentration in blood is 0.12 g/l and its biological survival (plasma T1/2) is 5 days.
利用方法
The reagent is designed for Flow Cytometry analysis. Working concentrations should be determined by the investigator.
保存方法
Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
安定性情報
Do not use after expiration date stamped on vial label.
レファレンス
• Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann·Rheum·Dis. 1980·Apr; 39(2):129‑34. <·PMID:·6966908·>
• Brinkmann V, Heusser CH: T cell‑dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors. Cell·Immunol. 1993·Dec; 152(2):323‑32. <·PMID:·8258141·>
• Franklin EC: Structure and function of immunoglobulins. Acta·Endocrinol·Suppl·(Copenh). 1975; 194:77‑95. <·PMID:·47690·>
• Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin·Chem. 1975·May; 21(6):667‑71. <·PMID:·1122610·>